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Parkinson's Disease News covers all significant new research, reports, books, and resources concerning Parkinson's Disease. Articles are chosen on the basis of their medical significance or potential interest. Our overwhelming priority is the facts, regardless of whether they contradict prevailing views or vested interests. Analysis and further information are provided either to explain the background or implications, or to balance misleading claims. If you notice errors or inadequacies, or dispute what is written, or want to propose articles, please e-mail mail@viartis.net.

                                           

 

15th June 2018 - New research

LRP10 - A NEW GENETIC FORM OF PARKINSON'S DISEASE

 CLICK HERE FOR A PRINTABLE OR WHITE BACKGROUND VERSION OF THIS ARTICLE

A new genetic form of Parkinson's Disease has been discovered called LRP10. A small proportion of cases of Parkinson's Disease have a genetic cause. Most of them make Parkinson's Disease more likely rather than inevitable. Genetic disorders normally occur due to inheritance, either autosomal recessive (from both parents) or autosomal dominant (from one parent), but can arise spontaneously. Having relatives with Parkinson's Disease does not mean that it has been inherited, because relatives can have similar environmental factors. For more information concerning genetic causes go to :  Genetic causes of Parkinson's Disease

The gene, which is called LRP10, is on Chromosome 14. The type of inheritance is unknown. This genetic form of Parkinson's Disease was found in Italian individuals and somebody from Taiwan but that does not mean that other nationalities are not affected. Of those people that had rare and potentially pathogenic variants, four of them had Parkinson's Disease, two of them had Parkinson's Disease with dementia, and two of them had Parkinson's Disease with dementia and Lewy bodies. The findings implicate LRP10 gene defects in the development of inherited forms of a-synucleinopathies. Being newly discovered there are no genetic tests for LRP10.

Reference : Lancet Neurology [2018] Jun 6 [Epub ahead of print] (M.Quadri, W. Mandemakers, M.M.Grochowska, R.Masius, H.Geut, E.Fabrizio, G.J.Breedveld, D. Kuipers, M.Minneboo, L.J.M.Vergouw, A.Carreras Mascaro, E.Yonova-Doing, E.Simons, T.Zhao)  Complete abstract   For more news go to Parkinson's Disease News

 

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THE COMPREHENSIVE GUIDE TO PARKINSON'S DISEASE

The Comprehensive Guide to Parkinson's Disease, which is fully referenced, and over 800 pages long, is the most comprehensive book concerning Parkinson's Disease. It includes the history of Parkinson 's Disease, famous people with Parkinson's Disease, the complete biochemisty of Parkinson's Disease,
its cytology and cytological effects, anatomy and anatomical effects, physiology and physiological effects, symptoms of every system in the body, the diagnosis methods (observational, technological, chemical), biochemical causes, all the toxic causes, all the genetic causes, all the pharmacological causes, all the medical disorders that cause Parkinson's Disease symptoms, its treatments (biochemical, pharmacological, surgical, natural, exercise methods, technological methods), including all those treatments that exist and all those treatments presently being developed, Parkinson's Disease organisations, Parkinson's Disease web sites, and books on Parkinson's Disease nursing. CLICK HERE FOR MORE DETAILS

 


 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 
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2018-06-15 23:25:39
 
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