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Parkinson's Disease News covers all significant new research, reports, books, and resources concerning Parkinson's Disease. Articles are chosen on the basis of their medical significance or potential interest. Our overwhelming priority is the facts, regardless of whether they contradict prevailing views or vested interests. Analysis and further information are provided either to explain the background or implications, or to balance misleading claims. If you notice errors or inadequacies, or dispute what is written, or want to propose articles, please e-mail mail@viartis.net.

                                           

 

8th August 2018 - New research

GARCINOL - A FUTURE MAO INHIBITOR FOR PARKINSON'S DISEASE

 CLICK HERE FOR A PRINTABLE OR WHITE BACKGROUND VERSION OF THIS ARTICLE

MAO inhibitors are often prescribed for Parkinson's Disease. MAO inhibitors help to maintain dopamine levels by inhibiting the enzyme Monoamine Oxidase (MAO). It is primarily low dopamine levels that cause Parkinson's Disease. The main MAO inhibitors in use are selegiline, rasagiline and safinamide. For more information go to : selegiline , rasagiline , safinamide . Researchers have assessed Garcinol, which originates from plant species. For more information go to : garcinol

The present study identified Garcinol as a potential candidate in the treatment of Parkinson's Disease by virtue of its exorbitant MAO-B inhibitory potential. The inhibitory potential is comparable to the known MAO-B inhibitors, which was evaluated using molecular docking technique.

Additionally, Garcinol was found to have potential as a COMT inhibitor, which the existing MAO inhibitors don't have. COMT inhibitors are another type of Parkinson's Disease drug. It was also found to have known antioxidant and anti-inflammatory potential.

Reference : Medical Hypotheses [2018] 117 : 54-58 (M.K.Mazumder, R.Paul, B.C.Phukan, A.Dutta, J.Chakrabarty, P.Bhattacharya, A.Borah)  Complete abstract   For more news go to Parkinson's Disease News

 

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THE COMPREHENSIVE GUIDE TO PARKINSON'S DISEASE

The Comprehensive Guide to Parkinson's Disease, which is fully referenced, and over 800 pages long, is the most comprehensive book concerning Parkinson's Disease. It includes the history of Parkinson 's Disease, famous people with Parkinson's Disease, the complete biochemisty of Parkinson's Disease,
its cytology and cytological effects, anatomy and anatomical effects, physiology and physiological effects, symptoms of every system in the body, the diagnosis methods (observational, technological, chemical), biochemical causes, all the toxic causes, all the genetic causes, all the pharmacological causes, all the medical disorders that cause Parkinson's Disease symptoms, its treatments (biochemical, pharmacological, surgical, natural, exercise methods, technological methods), including all those treatments that exist and all those treatments presently being developed, Parkinson's Disease organisations, Parkinson's Disease web sites, and books on Parkinson's Disease nursing. CLICK HERE FOR MORE DETAILS

 


 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 
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2018-08-08 13:36:05
 
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