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23rd August 2012 - New research
THE PREVALENCE OF NON-MOTOR SYMPTOMS IN PARKINSON'S DISEASE
Clinical Neurology and Neurosurgery [2012] Aug 16
[Epub ahead of print] (E.M.Khedr, N.A.El Fetoh, H.Khalifa, M.A.Ahmed, K.M.El Beh)
Complete abstract
The primary symptom of Parkinson's Disease is excessive muscle contraction. That
leads to the characteristic symptoms such as rigidity, tremor, and bradykinesia
(slowness of movement). However, muscles are involved in physiological functions
throughout the body. The dopamine deficiency that causes Parkinson's Disease
also directly affects the emotions. Consequently, non-motor symptoms of
Parkinson's Disease are very common.
The
non-motor symptoms that were found to most prevalent in Parkinson's Disease were
: disturbance of mood and cognition (87%), sleep disturbance and fatigue (78%),
gastrointestinal (76%), urinary (76%), sexual dysfunction (73%), cardiovascular
(70%). Perceptual problems and hallucinations are infrequent (10%) and are
usually due to Parkinson's Disease drugs, especially dopamine agonists, rather
than Parkinson's Disease itself. Dementia, which was found to be mostly mild,
occurred in around 22% of people with Parkinson's Disease. Although dementia
often eventually occurs in Parkinson's Disease, it has an entirely different
biochemistry from Parkinson's Disease. It is therefore not actually a
Parkinson's Disease symptom or inevitable in Parkinson's Disease. For a printable version of this article
click here.
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Parkinson's Disease News details
all significant new research, news reports, new books, and new resources
concerning Parkinson's Disease and those medical disorders that often coincide
with Parkinson's Disease. It is compiled from an analysis of all newly
published research, news reports, new clinical trials, all newly published
books, and new web sites. A summary and analysis of the new research are
provided, as well as links to the complete abstracts and news reports

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