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Parkinson's Disease News covers
all significant new research, reports, books, and resources concerning
Parkinson's Disease.
Articles are chosen on the basis
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8th August 2013 - New research
DIABETIC DRUG TO TREAT PARKINSON'S DISEASE
Journal of Clinical Investigation [2013] 123 (6) : 2730-2736 (I.Aviles-Olmos,
J.Dickson, Z.Kefalopoulou, A. Djamshidian, P.Ell, T.Soderlund, P.Whitton,
R.Wyse, T.Isaacs, A.Lees, P.Limousin, T.Foltynie)
Complete abstract
Exenatide, which is a type 2 diabetes treatment, has been found in clinical
trials to improve Parkinson's Disease. Exentaide was previously found to have
neuroprotective and neurorestorative properties. Exenatide differs
in pharmacological action
and chemical structure
from insulin.
For more information go to
Exenatide
People
with moderate Parkinson's Disease received subcutaneous injections of
Exenatide for a year.� Their Parkinson's Disease was compared after
overnight withdrawal of conventional Parkinson's Disease medication using
the Unified Parkinson's Disease Rating Scale (UPDRS). Exenatide was well
tolerated but weight loss was common. There were clinically relevant
improvements in Parkinson's Disease� motor and cognitive measures.
Exenatide treated patients had a mean improvement after one year on the
UPDRS of 2.7 compared with a mean decline of 2.2 points in controls.
The authors do not make
suggestions as to how the diabetes drug has effect in Parkinson's Disease. For a printable version of this article
click here.
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